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Abstract

The global population is increasing, with a predicted demand for 1250 million tonnes of animal-derived protein by 2050, which will be difficult to meet. Single-cell protein (SCP) offers a sustainable solution. This review covers SCP production mechanisms, microbial and substrate choices, and advancements in metabolic engineering and CRISPR-Cas. It emphasizes second-generation substrates and fermentation for a circular economy. Despite challenges like high nucleic acid content, SCP promises to solve the global nutrition problem.

Keywords

Single-cell proteinProduction (economics)PopulationCRISPRGlobal populationFermentationBiochemical engineeringBiotechnologyComputer scienceBiologyFood scienceEngineeringBiochemistryEconomics

Identifiers

Journal
npj Science of Food
Year
2024