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Butyric Acid from Probiotic Staphylococcus epidermidis in the Skin Microbiome Down-Regulates the Ultraviolet-Induced Pro-Inflammatory IL-6 Cytokine via Short-Chain Fatty Acid Receptor
Sunita Keshari, Arun Balasubramaniam, Binderiya Myagmardoloonjin, Deron R. Herr +2
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Abstract
on suppression of UVB-induced IL-6 production. These results demonstrate that butyric acid in the metabolites of fermenting skin probiotic bacteria mediates FFAR2 to modulate the production of pro-inflammatory cytokines induced by UVB.
Keywords
Staphylococcus epidermidisShort-chain fatty acidButyric acidMicrobiologyCytokineProbioticFatty acidIn vivoChemistryBiologyFermentationButyrateBacteriaBiochemistryStaphylococcus aureusImmunology
Identifiers
- Journal
- International Journal of Molecular Sciences
- Year
- 2019