Hive-shaped carbon nanotubes coated with MoSe₂ as an electrochemical sensor for cholesterol

Abstract

The study utilized transition metal chalcogenide, molybdenum diselenide (MoSe 2 ), for application in the field of bioelectrochemical sensing. The MoSe 2 was combined with carbon nanotubes (CNTs) by chemical vapor deposition to enhance the specific surface area and improve the detection sensitivity. To further increase the contact area between the electrolyte and the electrode, photolithography techniques were employed to fabricate hive-shaped CNTs, thereby enhancing the specific surface area. Next, cholesterol oxidase (ChO x ) was coated onto the electrode material, creating a cholesterol biosensor. Cyclic voltammetry was utilized to detect the concentration of cholesterol. The experiment involved segmented testing for cholesterol concentrations ranging from 0 μ M to 10 mM. Excellent sensitivity, low detection limits, and high accuracy were achieved. In the cholesterol concentration range of 0 μ M-100 μ M, the experiment achieved the highest sensitivity of 4.44 μ A μ M⋅cm -2 . Consequently, all data indicated that ChO x /MoSe 2 /CNTs functioned as an excellent cholesterol sensor in the study.

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Identifiers

DOI

10.1088/1361-6528/ad7141

PubMed

39221963

Journal

Nanotechnology

Year

2024