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Engineering of E. coli inherent fatty acid biosynthesis capacity to increase octanoic acid production
Zaigao Tan, Jong Moon Yoon, Anupam Chowdhury, Kaitlin Burdick +3
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Abstract
This work demonstrates the effectiveness of integration of computational strain design and experimental characterization as a starting point in rewiring metabolism for octanoic acid production. This result in conjunction with the results of other studies using OptForce in strain design demonstrates that this strategy may be also applicable to engineering E. coli for other customized bioproducts.
Keywords
BiosynthesisProduction (economics)Metabolic engineeringFood scienceBiotechnologyFatty acid
Identifiers
- PubMed
- 29619083
- Journal
- Biotechnology for Biofuels
- Year
- 2018