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This study examines the metabolic regulation of E. coli and its mutants under various carbon and nitrogen limitations in a continuous culture, with implications for microbial desalination cells.

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Abstract

Key findings

  • The gdhA mutant showed increased glucose uptake and gluconeogenesis under nitrogen limitation.
  • The glnL mutant exhibited reduced glutamine synthetase activity and increased ammonium production under carbon limitation.
  • The gltB mutant displayed impaired citrate synthase activity and reduced growth rate under both carbon and nitrogen limitations.

Keywords

Escherichia coliMutantNitrogenCarbon fibersMicrobiologyProcess (computing)

Identifiers

DOI
10.1186/1475-2859-9-8
Journal
Microbial Cell Factories
Year
2009