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In silico-guided engineering of Pseudomonas putida towards growth under micro-oxic conditions
Linde F. C. Kampers, Ruben Heck, Stefano Donati, Edoardo Saccenti +5
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Abstract
We demonstrated the value of combining in silico approaches, experimental validation and adaptive laboratory evolution for microbial design by making the strictly aerobic Pseudomonas putida able to grow under micro-oxic conditions.
Keywords
Pseudomonas putidaIn silicoBiochemical engineeringBiotechnologyComputational biologyMicrobiology
Identifiers
- PubMed
- 31640713
- Journal
- Microbial Cell Factories
- Year
- 2019