Flagellated bacterial porter for in situ tumor vaccine
Haiheng Xu, Yiqiao Hu, Jinhui Wu
AI summary
100% confidenceMES research in bacteria, wastewater. Cancer immunotherapy, which use the own immune system to attack tumors, are increasingly pop...
Generated by MESSAI extraction pipeline · review against source PDF
Reported parameters
No values extracted from this paper yet.
No 3D model is mapped to this paper yet. Parameter ranges above still place reported values on the literature distribution.
Abstract
Cancer immunotherapy, which use the own immune system to attack tumors, are increasingly popular treatments. But, due to the tumor immunosuppressive microenvironment, the antigen presentation in the tumor is limited. Recently, a growing number of people use bacteria to stimulate the body’s immunity for tumor treatment due to bacteria themselves have a variety of elements that activate Toll-like receptors. Here, we discuss the use of motility of flagellate bacteria to transport antigens to the tumor periphery to activate peritumoral dendritic cells to enhance the effect of in situ tumor vaccines.
Keywords
Identifiers
- Journal
- Microbial Cell
- Year
- 2022