Marine-freshwater prokaryotic transitions require extensive changes in the predicted proteome

Abstract

The marked changes at the level of protein amino acid composition and pI provide a tool to predict the preferred habitat of a culture or a metagenome-assembled genome (MAG). The exact physiological explanation for such variations in the pIs and electrostatic surface potentials is not known yet. However, these changes might reflect differences in membrane bioenergetics derived from the absence of significant Na + concentrations in most freshwater habitats. In any case, the changes in amino acid composition in most proteins imply that a long evolutionary time is required to adapt from one type of habitat to the other.

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Identifiers

DOI

10.1186/s40168-019-0731-5

PubMed

31439042

Journal

Microbiome

Year

2019