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Abnormal resting state effective connectivity within the default mode network in major depressive disorder: A spectral dynamic causal modeling study
Liang Li, Baojuan Li, Yuanhan Bai, Wenlei Liu +9
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Abstract
These findings suggest that the reduced excitatory causal influence of the left parietal cortex is the key alteration of the DMN in patients with MDD, and the disrupted causal influences that parietal cortex exerts on the posterior cingulate cortex is responsive to antidepressant treatment.
Keywords
Default mode networkPosterior parietal cortexPosterior cingulateMajor depressive disorderNeuroscienceAnterior cingulate cortex
Identifiers
- PubMed
- 28729938
- Journal
- Brain and Behavior
- Year
- 2017