A Novel CD105 Determination System Based on an Ultrasensitive Bioelectrochemical Strategy with Pt Nanoparticles
Suyun Zeng, Sujun Wang, Li Wang, Lihua Yang +2
AI summary
70% confidenceCD105 is a well-known tumor metastasis marker and useful for early monitoring of metastasis and cancer relapse. It is important to generate rapid, reliable and precise analytical information regarding CD105 levels.
Generated by MESSAI extraction pipeline · review against source PDF
No 3D model is mapped to this paper yet. Parameter ranges above still place reported values on the literature distribution.
What they did
- System
- MBES
What worked
No outcome metrics extracted yet.
Abstract
CD105 is a well-known tumor metastasis marker and useful for early monitoring of metastasis and cancer relapse. It is important to generate rapid, reliable and precise analytical information regarding CD105 levels. To establish a simple, selective and sensitive detection method, we prepared an immunosensor with novel bioconjugates based on Pt nanoparticles, thionin acetate and antibodies. The proposed immunosensor displayed a broader linear response to CD105, with a working range of 1.3 to 200.0 ng/mL and a detection limit of 0.9 ng/mL under optimal conditions. Moreover, the studied immunosensor exhibited high sensitivity, fast analysis and adequate stability. The proposed methodology could readily be extended to other clinical- or environment-related biospecies.
Keywords
Identifiers
- Journal
- Sensors
- Year
- 2012