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The paper presents a method for controlling spacing and signal amplification in DNA-CT-based bioelectrochemical devices, enabling multimarker and functional assays from crude cell lysates.

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Abstract

Key findings

  • DNA-CT-based bioelectrochemical devices can be used for multimarker and functional assays from crude cell lysates.
  • Controlling spacing in DNA-CT-based bioelectrochemical devices is crucial for signal amplification and assay sensitivity.
  • Signal amplification in DNA-CT-based bioelectrochemical devices can be achieved through optimized spacing and functionalization of the DNA-CT layer.

Keywords

DNALysisBiomoleculeBiosensorCellComputational biology

Identifiers

Journal
Current Opinion in Electrochemistry
Year
2019