Recent Advances on Electrochemical Biosensing Strategies toward Universal Point of Care Systems.

Abstract

A number of very recently developed electrochemical biosensing strategies are promoting electrochemical biosensing systems into practical point-of-care applications. Focus of research endeavors in biosensing community has transferred from detection of a specific analyte to the development of general biosensing strategies that can be applied for a single category of analytes, such as nucleic acid, protein and cell. In this review, we describe most recent cutting-edge researches on electrochemical biosensing strategies. These described developments resolved critical challenges on application of electrochemical biosensors to the practical point-of-care systems, such as rapid readout, simple biosensor fabrication method, ultra-high detection sensitivity, direct analysis in complex biological matrix and multiplexed targets analysis. This review provides general guidelines both for scientists in the biosensing research community and for the biosensor industry on development of point-of-care system, benefiting global healthcare.

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Identifiers

DOI

10.1002/anie.201901879

Journal

Angewandte Chemie International Edition

Year

2019