An "on-off-on" self-powered biosensor based on enzyme-free amplification for detection of three biomarkers.
Jiajun Zhan, Futing Wang, Yujin Li, Jingxian Li +4
AI summary
75% confidenceThis MES study investigates Catalytic hairpin assembly, Enzyme biofuel cells, Self-powered biosensor. The research focuses on system optimization and characterization.
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Abstract
MicroRNAs (miRNAs), a type of small non-coding RNA sequences, are very important biomarkers and are involved in various physiological processes, such as cell proliferation, growth, differentiation, and apoptosis. Many reports have shown that miRNAs are closely associated with a variety of diseases, including neurodegenerative diseases and cancer. Currently, researchers have developed various methods for miRNAs detection, such as fluorescence, surface-enhanced Raman scattering, electrochemiluminescence, and electrochemical sensing. The detection of multiple miRNAs is significant for the diagnosis of diseases. However, it is rare for a single biosensing system to ultra-sensitively detect multiple miRNAs.
Keywords
Identifiers
- PubMed
- 40701703
- Journal
- Analytica chimica acta
- Year
- 2025