Toward Next-Generation Semiartificial Photosynthesis: Multidisciplinary Engineering of Biohybrid Systems.
AI summary
75% confidenceThis review addresses the critical knowledge gap in optimizing the three core components of semiartificial photosynthesis: photosensitizers, microbial partners, and solar energy input. It provides a structured overview of multidisciplinary strategies aimed at developing next-generation biohybrid platforms (Biohybrids 2.0) to enhance efficiency, stability, and scalability.
Generated by MESSAI extraction pipeline · review against source PDF
Reported parameters
No values extracted from this paper yet.
No 3D model is mapped to this paper yet. Parameter ranges above still place reported values on the literature distribution.
Abstract
Semiartificial photosynthesis has witnessed remarkable progress over the past decade, driven by the integration of diverse biological systems with synthetic materials, ushering in the first generation of biohybrid platforms (Biohybrids 1.0). While previous reviews have extensively examined whole-cell biohybrid systems and the fundamental mechanisms underlying solar-to-chemical energy conversion, a critical knowledge gap remains in the rational optimization of their three core components: photosensitizers, microbial partners, and solar energy input. These interdependent elements collectively determine the efficiency, stability, and scalability of biohybrid platforms. To address this gap, this review offers a comprehensive and structured overview of multidisciplinary strategies for the development of next-generation biohybrid platforms (Biohybrids 2.0). It highlights recent advances in photosensitizer design, microbial selection and engineering, energy sources and conversion strategies, interface control and optimization, and state-of-the-art characterization methodologies, while providing a comprehensive summary of a diverse and expanding range of emerging applications. The review also offers a critical appraisal of current limitations and proposes forward-looking research directions that may enable transformative progress toward Biohybrids 3.0. Altogether, this integrative perspective outlines a coherent framework for the rational design of robust, efficient, and application-ready semiartificial photosynthetic systems for real-world and industrial-scale deployment.
Key findings
- Previous research has extensively covered whole-cell biohybrid systems but lacks rational optimization strategies for their interdependent core components.
- The development of Biohybrids 2.0 requires integrated advancements in photosensitizer design, microbial engineering, and interface control.
- Emerging applications in solar-to-chemical energy conversion depend on the collective performance of biological and synthetic materials.