In-Vivo Glucose Assay on the Living Fish Brain Molecule and Human Urine by Using of Bismuth-Immobilized Carbon Nanotube Paste Electrode

Abstract

Background/Objective: In-vivo diabetes detection of glucose were sought using square-wave anodic stripping voltammetry (SW), with bismuth-immobilized carbon nanotube paste electrode (BCE). Methods: The optimum analytical results indicated sensitive peak signals on the BCE. The raw voltammogram was approached within the 1 mgL-1-14 mgL-1 and 10 ugL-1-140 ugL-1, detection limits with preconcentration times of 100 and 200 sec. Results: The relative standard deviation was 0.02 % (n = 15) of 10.0 mgL-1 under optimum conditions. The analytical detection limit (S/N) was attained at 8 ugL-1. The handmade microsensor was directly used in vivo on the living fish brain and human urine.Conclusion: The method was applied at real time in vivo, without requiring any pretreatment and other ionic electrolyte solutions. It can be used for medicinal and other materials requiring biological-fluid detection in real time. This study was designed to be suitable for real-time unmanned remote diagnosis and therapeutic drug injection into the body, micro-needle long-term administration, wearable artificial skin tattoo sensor, and real-time control. In addition, the glasses monitor was designed to be suitable for multitasking and multi-user control.

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Identifiers

DOI

10.20944/preprints202410.0990.v1

Journal

Preprints.org

Year

2024