Investigating the catalytic and antimicrobial properties of ternary cesium/polyethylene glycol-SrO supported by molecular docking and DFT analysis.
Misbah Tariq, Muhammad Imran, Ali Haider, Iram Shahzadi +5
AI summary
70% confidenceThis study synthesized ternary nanocomposites of SrO doped with PEG and varying amounts of Cs, and evaluated their catalytic activity in degrading methyl orange dye and antimicrobial properties against E. coli. The results showed that the 2% Cs/PEG-SrO sample exhibited efficient catalytic activity, while the 4% Cs/PEG-SrO sample demonstrated significant bactericidal efficacy against E. coli. Computational findings supported the antimicrobial effectiveness of Cs/PEG-SrO by inhibiting DNA gyrase in E. coli.
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Abstract
This study explores the use of ternary system nanocomposites to degrade methyl orange (MO) dye in water as well as assesses their antibacterial properties. For this purpose, the co-precipitation process was adopted to synthesize strontium oxide (SrO) doped with a fixed amount (3 wt%) of polyethylene glycol (PEG) as a capping agent, and various weight ratios (2 and 4 wt%) of cesium (Cs) were added to the binary system (PEG-SrO). Advanced characterization techniques were employed to analyze the various properties of the resulting materials. XRD unveiled the cubic crystal structure of SrO, while TEM revealed randomly oriented nanorods in the pristine sample. The optimum sample (2% Cs/PEG-SrO) demonstrated efficient catalytic activity (CA) in degrading MO dye. The 4% Cs/PEG-SrO sample showed significant bactericidal efficacy against Escherichia coli ( E. coli ), exhibiting inhibition zones ranging from 2.05 to 6.15 mm at higher concentrations. Furthermore, the computational findings align with the experimental data, offering strong evidence for the microbial effectiveness of Cs/PEG-SrO in hindering DNA gyrase in E. coli .
Keywords
Identifiers
- PubMed
- 41777820
- Journal
- RSC advances
- Year
- 2026