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75% confidence

This MES study investigates Anaerobic digestion, Bioreactor, Microbial analysis. Key performance metrics include COD removal.

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Coulombic efficiency5%

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Abstract

This study compared the treatment of high-salinity pharmaceutical wastewater by using Continuous Stirred Tank Reactor (CSTR), Upflow Anaerobic Sludge Blanket (UASB), and two-phase Cascade Energy Anaerobic Reactor (CEAR) with bioaugmentation (Bacillus altitudinis K3). The CEAR significantly increased methane production through separating acidogenic and methanogenic phases, achieving a 9.70% to 23.10% higher methane content than other systems. With the increase in salinity and organic loading rate, the chemical oxygen demand (COD) removal efficiency of CSTR decreased significantly. In contrast, both the UASB and CEAR reactors maintained a high COD removal rate above 85%. Bioaugmentation can alleviate salt inhibition, enhanced microbial activity, and enriched salt-tolerant methanogens. The CEAR combined with bioaugmentation offered an effective strategy for methane recovery from high-salinity pharmaceutical wastewater.

Keywords

Anaerobic digestionBioreactorMicrobial analysisSalinity stress

Identifiers

PubMed
41605273
Journal
Bioresource technology
Year
2026