Bacterial–Viral Coinfections in Cervical Cancer

Abstract

Cervical cancer is a common malignancy among women, especially in the developing world. Human papillomavirus (HPV) is the necessary cause of cervical cancer, though a big proportion of women who get the infection recover without developing cervical lesions. There are certain bacterial that have been shown to be associated with development of premalignant cervical lesions and their progression to invasive cancer. Chlamydia trachomatis (CT) and Treponema pallidum are considered potential cofactors to HPV infection and persistence; hence development of cervical cancer. The association between these coinfections and cervical lesions is thought to be based on their shared routes of transmission and the need for a breach in the continuity of the epithelium.

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Identifiers

DOI

10.5772/intechopen.115009

Journal

Bacterial, Viral, Fungal and Parasitic Coinfections

Year

2024