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MES research in wastewater, bioelectrochemical. Nonalcoholic fatty liver disease (NAFLD) has become the world's largest chronic liver disease, while...

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Abstract

Nonalcoholic fatty liver disease (NAFLD) has become the world's largest chronic liver disease, while there is still no specific drug to treat NAFLD. Traditional Chinese Medicine (TCM) have been widely used in hepatic diseases for centuries in Asia, and TCM’s holistic concept and differentiation treatment of NAFLD show their advantages in the treatment of this complex metabolic disease. However, the multi-compounds and multi-targets are big obstacle for the study of TCM. Here, we summarize the pharmacological actions of active ingredients from frequently used single herbs in TCM compounds. The combined mechanism of herbs in TCM compounds are further discussed to explore their comprehensive effects on NAFLD. This article aims to summarize multiple functions and find the common ground for TCM treatment on NAFLD, thus providing enrichment to the scientific connotation of TCM theories and promotes the exploration of TCM therapies on NAFLD.

Keywords

Nonalcoholic fatty liver diseaseTraditional Chinese medicineDiseaseTraditional medicineFatty liverChinese herbs

Identifiers

DOI
10.1186/s13020-021-00469-4
Journal
Chinese Medicine
Year
2021