Evaluation of brain bioelectrical activity during xenon-oxygen mixture inhalation

Abstract

Xenon is an inert gas used like inhalational anesthetic during different surgeries, including high-risk operations and for pain treatment caused by different factors. If concentration of the gas is less than 50 %, or the duration of the procedure is very short, no consciousness depression occurs. 20 healthy persons from 22 to 30 years old were undergone xenon/oxygen inhalation with concentration 70/30 % respectively for 3 minutes. Electroencephalography (EEG) was recorded before, during and 30 minutes later the procedure. For the data processing spectral analysis was used. Statistical analysis was performed by Wilcoxon and Page tests. As a result, significant increase in slow wave activity and reduction in alpha-rhythm activity were observed during and after the procedure as well as repartition of activity zones in brain similar to physiological sleep. This fact may be used in conduction of treatment and diagnostics procedures.

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Identifiers

DOI

10.21320/1818-474x-2019-1-94-99

Journal

Annals of Critical Care

Year

2019