Antibiotic resistances from slaughterhouse effluents and enhanced antimicrobial blue light technology for wastewater decontamionation

Abstract

Abstract The global spread of antimicrobial resistances is mainly due to the emission of antibiotic-resistant bacteria, antibiotic resistance genes, facultative pathogenic bacteria, and antimicrobial resistance causing substances in human and animal waste into the environment. Innovative strategies are sought to intervene decentrally or centrally at sources of the emergence and spread of hygienically relevant bacteria. In this study, the dissemination of facultative pathogenic bacteria and antibiotic resistance genes of clinical relevance are monitored in the raw effluents from poultry and pig slaughterhouses in combination of some conventional wastewater treatments on site. As an innovation step, the antimicrobial blue light (aBL) in combination with a porphyrin-based photo-enhancer is investigated for decontamination purpose. Facultative pathogenic bacteria from the clinically significant ESKAPE group are used as reference bacteria and examined for the effectiveness of this inactivation strategy. Beside the directed analyses with reference bacteria, a successful application of the combinatory light-based method was also demonstrated using raw sewage from slaughterhouse.

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Identifiers

DOI

10.21203/rs.3.rs-2770853/v1

Journal

Research Square

Year

2023