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Lab-on-chip MFC · engineering redesign dossier · July 2026

Device redesign · review → fix → render

A fuel cell on a chip, taken apart and made honest.

The homepage's lab-on-chip render, put through an engineering review and rebuilt so it survives a bioelectrochemist's read — three blocker-level fixes, an honest reaction, and the volume restored — without leaving the aesthetic. The exploded stack below is the real layer set.

Device
Membraneless µMFC
Reaction
substrate → CO₂ + e⁻
Power
µW–mW · harvested
Stack
L1→L6 + optional PEM

Exactly what ships on the apps/site homepage — the real R3F stage, rendered headless. Everything below is a static breakdown of the same device, so you can inspect it without deploying.

Rendered exploded view of the corrected lab-on-chip microbial fuel cell on the MESSAI homepage
apps/site · homepage 3D tour · stage 7/9

Each film is drawn from the device's real material set. The table reads top film (L1) to chassis (L6); the PEM is the optional separator between L3 and L4 and is absent in the membraneless hero mode.

L1 · ITO optical windowITO (In₂O₃:Sn)L2 · Graphene-foam bioanodeGraphene foam · rGOL3 · Co-laminar Tesla channelBiofilm · agar · PDMS channelPEM · optionalComposite PEM (Nafion-class)L4 · Air-breathing carbon cathodeCarbon · MoS₂ · stainless · PTFEL5 · Magnetite (Fe₃O₄) mixerMagnetite (Fe₃O₄) · soft-magnetic ridgesL6 · Basalt-fibre chassisBasalt-fibre composite · ferritefeed · substrate ▸e⁻ anode ▸▸ CO₂ · effluent▸ µW telemetry
The stack in its default membraneless mode: substrate feeds the co-laminar channel, the graphene-foam bioanode collects electrons, CO₂ and effluent leave, and the dry copper coil under the air-cathode picks up µW-scale telemetry. The PEM is drawn dashed because it is an optional separator, not part of the hero mode.
LayerComponentMaterialFeatureRoleWhy
L1 / 6 · top filmITO optical windowITO (In₂O₃:Sn)Transparent conductor · optical accessWindow · current path · readoutA transparent conductive-oxide lid that closes the cell, carries current, and lets light in for microscopy and optical readout — the credible read of the old "perovskite" cover.
L2 / 6 · conductorGraphene-foam bioanodeGraphene foam · rGOHoneycomb lattice · biofilm scaffoldBioanode current collectorA 3-D graphene-foam / rGO sheet is the current-collecting skin the electroactive biofilm grows on — huge conductive surface area, unlike hydrophobic flat graphene.
L3 / 6 · bioreactorCo-laminar Tesla channelBiofilm · agar · PDMS channelMembraneless co-laminar · Tesla self-pump · LED readoutBiocatalysis · rectification · sensingThe living heart, run membraneless: two co-flowing streams stay split by laminar flow, a Tesla valve rectifies evolved gas into net self-pumping, and LEDs read the cell out optically.
optional · between L3–L4Composite PEM (optional)Composite PEM (Nafion-class)Toggleable · proton transportOptional separationDrop this proton-exchange membrane in to run a separated cell; leave it out to run membraneless on the co-laminar streams. That toggle is what makes the slide multi-use.
L4 / 6 · electrodeAir-breathing carbon cathodeCarbon · MoS₂ · stainless · PTFEORR · metallic collector · dry Cu coilOxygen reduction · current pathAn air-breathing carbon cathode does oxygen reduction; a stainless current-collector (fingers + bus bar) is the metallic current path, and a DRY copper coil sits beneath for induction. No wetted copper — Cu is antimicrobial and corrodes.
L5 / 6 · transportMagnetite (Fe₃O₄) mixerMagnetite (Fe₃O₄) · soft-magnetic ridgesHerringbone micromixer · EET boostMass transport · electron transferA magnetite layer boosts extracellular electron transfer and carries a staggered-herringbone micromixer that folds the co-laminar feed to beat diffusion limits. Replaces the non-physical "magnetic heat sink".
L6 / 6 · chassisBasalt-fibre chassisBasalt-fibre composite · ferriteSustainable substrate · ferrite flux returnChassis · magnetic return · takeoutA basalt-fibre composite is the inert, cheap, sustainable structural base; a thin ferrite tile gives the pickup coil a real magnetic return, and edge pads take current off-chip.

The original looked great but conflated three operating modes and carried two hard materials errors. Each was fixed through geometry, not by dropping the aesthetic.

Blocker · materials
Copper coil cathode→Air-cathode + dry Cu coil

Bare copper in a wetted cell is antimicrobial and corrodes, leaching Cu²⁺ that poisons the biofilm. Copper is now only the dry, encapsulated pickup coil — the wetted cathode is air-breathing carbon.

Blocker · physics
Magnetic heat sink→Magnetite (Fe₃O₄) micromixer

A µW chip near ambient has no heat load, and magnetism ≠ cooling. Repurposed to a real function: an Fe₃O₄ layer that boosts electron transfer and hosts a staggered-herringbone mixer.

Fix · materials
Paramagnetic basalt→Basalt-fibre chassis

“Magnetic basalt” isn't a real functional material. Kept as a sustainable structural substrate (basalt-fibre composite); the magnetic return path is a proper ferrite backing.

Fix · correctness
CO₂ · H⁺ in→Substrate in → CO₂ out

An MFC emits CO₂ from anodic oxidation — it isn't CO₂-fed (that would be electrosynthesis, which consumes power). The feed is now organic substrate; CO₂ + effluent leave.

Fix · stability
Perovskite · ITO→ITO optical window

A halide-PV perovskite is lead-bearing and decomposes in hours in a wet, salty, biological cell. Reframed as the transparent conductive-oxide window it credibly is.

Fix · materials
Graphene · TMDs (anode)→Graphene-foam anode

Pristine 2D graphene barely colonises; the real performer is 3D foam/aerogel. And MoS₂/TMDs are cathode catalysts — they moved to L4, where they belong.

The first rigor pass flattened the mid-stack — the bright copper slab became matte carbon, tall fins became short studs. Volume was restored through rigorous geometry, not by reverting.

Where the dimensionality lives now

  • Staggered-herringbone micromixer — the canonical passive µmixer: metallic chevrons whose handedness flips every few cells. Strong relief and shadow, and more novel than the fins it replaced.
  • Stainless current-collector — fingers + bus bar across the carbon cathode: metallic, light-catching, the real current path — no wetted copper.
  • Thicker slabs — anode, cathode, magnetite and chassis given more body so the exploded stack reads chunky again.

Added for credibility

  • Ag/AgCl reference electrode — on-chip, for 3-electrode operation: resolves anode and cathode potentials independently. Its absence is a tell that a design isn't real electrochemistry.
  • Membraneless co-laminar — foregrounded as the hero mode (two co-flowing streams, no membrane); the PEM is the optional separator, drawn dashed in the stack above.

Defensible upgrades if the stage is ever expanded, recorded in the repo's design-rationale doc.

  • Interdigitated microelectrode array — generation/collection bioanode, the standard microfab approach at this scale.
  • Integrated O₂ / pH microsensors — closes the biosensing loop and gives the LEDs a real optical-readout job.
  • Supercap + cold-start PMIC → burst telemetry — the honest self-powered-node path; continuous µW export is loss-dominated.
  • Optogenetic LED control — if engineered phototrophs are introduced, the LEDs can drive gene expression, not just read out.
apps/site/src/react/systems/configurations.tsxthe MicrofluidicChip model — rebuilt
apps/site/src/react/MesMorphStage.tsxstage caption — made honest
apps/site/src/react/systems/lab-on-chip-design.mdnew · device rationale + guardrails
apps/site/src/react/systems/README.mdnew · 3D aesthetic conventions

Branch claude/website-redesign-owkin-wlui0r · PR #662 · commits c1126922 (rigor) + c5305509 (volume). This page is a static mirror of that work — the stack diagram and layer table above are a re-creation of the artifact's interactive explorer, the plate up top is the actual render.

Sources: Branch claude/website-redesign-owkin-wlui0r · PR #662 · commits c1126922 (rigor) + c5305509 (volume) · apps/site/src/react/systems/lab-on-chip-design.md · render captured headless from the apps/site homepage 3D tour, stage 7/9